Cut Heart Disease In Half By Lowering Three Risk Factors

See on Scoop.itiMaritha

RedOrbit Cut Heart Disease In Half By Lowering Three Risk Factors RedOrbit A new research review published by The Lancet from the Harvard School of Public Health and Imperial College London has found that blood pressure, cholesterol, and blood…

See on


Checking up on Dr. Google: How the search giant has tackled health and wellness | mobihealthnews

See on Scoop.itiMaritha

Google made big news recently when it announced Google Calico, a new venture that would apply “some longer term, moonshot thinking around healthcare and biotechnology,” putting the minds at Google toward the problems of aging and illness.

Calico is far from Google’s first venture into health or wellness, however. The company’s (ultimately failed) PHR venture Google Health was one high profile example, as were 3D anatomy-viewer Google Body and Google Flu Trends. The company has always had a background participation in activity tracking, debuting an Android app called MyTracks in 2009, and incorporating passive activity tracking into first Google Now and then the Android OS in general. And perhaps most importantly, Google has introduced health-related features into its original core offering: search. As well it should, since Pew data indicates that eight in 10 health inquiries start at a search engine like Google.

See on

Eat a Healthy Diet and Drink Wisely to Postpone Dying If You Survived a Myocardial Infarction

See on Scoop.itiMaritha

The Mediterranean diet as the most likely dietary model to provide protection against CHD.  Increasing adherence to the Mediterranean diet has been consistently beneficial for prevention of major chronic diseases, including fatal and nonfatal CHD, as well as all-cause mortality.

 In 4098 participants in the Nurses’ Health Study who survived an initial MI.  average dietary quality improved only marginally post-MI among the highly educated health professionals

Nevertheless, for participants who increased the diet/nutrition score, there was a 29% reduction in all-cause mortality and a 40% reduction in cardiovascular mortality. The AHEI2010 diet score used includes 11 components: vegetables, fruits, nuts and legumes, red meat and processed meats, sugar-sweetened beverages, alcohol, polyunsaturated fat, trans fat, omega-3 fat, whole grains, and sodium intake.

Many of the recommendations regarding these foods and nutrients are similar to the traditional Mediterranean diet: high consumption of whole grains, fruits, and vegetables; substantial intake of protein from plant sources (nuts and legumes); moderate intake of polyunsaturated fat; fish as a source of omega-3 fatty acids; and alcohol; and a low consumption of trans fat, meat and meat products, and sugar-sweetened beverages.

See on

For Some Cancer Patients, Personalized Medicine Has Arrived

See on Scoop.itiMaritha

New tools for analyzing genes are allowing doctors to personalize treatment for some lung cancer patients.


Imagine your doctor being able to scan your DNA from a biopsy and pinpoint the medicine that will work best for you. This type of high-tech approach is a clinical reality for advanced lung cancer at The Ohio State Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James).


The technology, known as next generation “multiplex” gene sequencing, analyzes 50-plus genes in DNA extracted from a tumor biopsy for particular genetic mutations.


Previous technology required pathologists to analyze one mutation per tube in a sequencing reaction, but next-generation genome sequencing assesses more than 2,500 mutations in a single reaction. 


Knowing which mutations are present in lung tumors can help doctors tailor a patient’s treatment to the unique genetic features present in his or her cancer cells.


The knowledge can also help in the development of new drugs that target previously unrecognized gene mutations in lung tumors. I often compare these genes to the gas pedal in a car — when activated, these genes make the cancer grow. By breaking the linkage between the gas pedal and the motor (or interfering with these “driver” mutations) with specific targeted drugs, doctors can stop this growth and often make the cancer shrink.


That’s especially important in lung cancer because the majority of patients with this disease are diagnosed in the later stages, meaning it’s important to start effective therapies quickly.


For example, a patient could be given a standard chemotherapy and expect a 25- to 30- percent response rate/shrinkage of a tumor. But if the treatment team knows that a patient has a mutation in a gene called EGFR, we can offer him or her a pill (erlotinib and afatinib are approved for this use in the United States), which has a 75-percent response rate and fewer side effects.


Gene sequencing is now considered the standard of care for stage-4 lung cancer patients at The OSUCCC – James and a handful of other centers across the United States — and several clinical trials evaluating molecular targeted therapies for patients with stage-3 lung cancers will soon start at The OSUCCC – James.



Lung cancer remains the number one cause of cancer death in the United States, and in the world, among both men and women. More than 200,000 cases are diagnosed annually in the United States. Each year during the month of November, physicians and others observe lung cancer awareness month, which sheds light on this terrible disease.

See on

Blog at

Up ↑